Each mL of ophthalmic solution contains sodium hyaluronate 3 mg, respectively.
It has a pH of 6-7 and an osmotic pressure ratio of 0.9-1.1. Excipients/Inactive Ingredients: Hialid Mini also contains ε-aminocaproic acid, disodium edetate hydrate as additives.
Action
Pharmacology:Mechanism of Action: Sodium hyaluronate is bound to fibronectin and accelerates the adhesion and extension of epithelial cells. It also has an excellent water-holding property because each sodium hyaluronate molecule can retain many water (H2O) molecules. Acceleration of Corneal Wound Healing: Topical application of sodium hyaluronate ophthalmic solution accelerates the wound healing of corneal epithelium in rabbits. Acceleration of Corneal Epithelial Extension: Sodium hyaluronate accelerates the extension of corneal epithelial cells in isolated strips of cultured rabbit cornea. Prevention of Corneal Drying: When applied to isolated strips of rabbit cornea, sodium hyaluronate is significantly more effective than artificial tears in preventing corneal drying.
Indications/Uses
Relief of symptoms associated with dry eyes.
Dosage/Direction for Use
For ophthalmic use only.
Usually, instill 1 drop a time 5-6 times daily. The dosage may be adjusted according to the patient's symptoms.
Hialid 0.1% ophthalmic solution should be used first. If the effect is insufficient, then Hialid Mini 0.3% ophthalmic solution may be administered.
Adverse Reactions
If the following adverse reactions or symptoms occur, discontinue Hialid Mini and consult a physician.
Adverse Reactions: Blepharitis, eyelid dermatitis, itching, irritation, conjunctivitis, conjunctival infection, corneal lesion eg, keratitis superficialis diffusa, eye discharge, foreign body sensation in eye, eye discharge, eye pain.
The tip of the eyedropper must not come into contact with the eyes at the time of application.
Discard first 1 or 2 drops (in order to eliminate fragments of container possibly contaminated at opening).
Use Hialid Mini only once after opening the vial.
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